Signs and Symptoms of PID

What are Primary Immunodeficiency symptoms?

• Infections that are unusually persistent, hard to treat, or require IV antibiotics.

• Infections caused by uncommon organisms (opportunistic infections), such as tuberculosis-like bacteria.

• Two or more deep-seated infections, such as septicemia.

• Persistent fungal (candida) infections in the mouth (thrush) or on the skin.

• Recurrent viral infections (herpes, warts, cold)

Some other signs are:

• Recurrent, deep skin or organ abscesses.

• Chronic rashes or unusual skin problems, sometimes with atopic (allergic) disorders such as eczema or asthma.

• Hearing loss (in some syndromic PIDs).

• Severe or unusual allergic reactions.

• A family history of primary immunodeficiency.

What are oral manifestations of PID?

• Recurrent and severe gum disease (periodontitis), sometimes aggressive enough to cause early tooth loss.

• Chronic or recurring mouth sores or ulcers.

• Persistent thrush (oral candida infection).

• Increased risk for dental cavities/caries due to changes in oral bacteria, gum disease, or reduced saliva flow.recurrent oral ulcers, gingivitis, and delayed tooth eruption.

How is PID diagnosed?

Diagnosis typically involves blood tests, immunological assessments, and patient history to identify specific deficiencies.

Can PID affect children?

Yes, primary immunodeficiency can manifest in childhood with various symptoms.

Is treatment available for PID?

Yes, treatments include immunoglobulin therapy and antibiotics to manage infections.

What should I do if I suspect PID?

Consult a healthcare professional for evaluation and potential testing if PID is suspected.